Acetyl-L-Carnitine
Also indexed as: Acetylcarnitine, ALC, L-Acetyl-Carnitine
Acetyl-L-carnitine is similar in form to the amino acid L-carnitine and also has some similar functions, such as being involved in the metabolism of food into energy. The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.
Where is it found?
Acetyl-L-carnitine is a molecule that occurs naturally in the brain, liver, and kidney. It is also available as a dietary supplement.
Acetyl-L-carnitine has been used in connection with the following conditions (refer to the individual health concern for complete information):
| Science Ratings | Health Concerns |
|---|---|
 |
Age-related cognitive decline |
 |
Alzheimer’s disease Cerebellar ataxia, degenerative Depression (for elderly people) Down’s syndrome Erectile dysfunction (in combination with L-carnitine) Fibromyalgia Macular degeneration (in combination with fish oil and coenzyme Q10) Type 1 diabetes Type 2 diabetes |
 |
Amenorrhea Male infertility Peripheral neuropathy |
| Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit. |
|
Who is likely to be deficient?
Acetyl-L-carnitine levels may decrease with advancing age. However, because it is not an essential nutrient, true deficiencies do not occur.
How much is usually taken?
Most research involving acetyl-L-carnitine has used 500 mg three times per day, though some research has used double this amount.1
Are there any side effects or interactions?
Side effects from taking acetyl-L-carnitine are uncommon, although skin rash, increased appetite, nausea, vomiting, agitation, and body odor have been reported in people taking acetyl-L-carnitine.2 3
Are there any drug
interactions?
Certain medicines may interact with acetyl-L-carnitine. Refer to drug interactions for a list of those medicines.
References
(To view, roll mouse over the "References" heading; to hide, click on the heading)
Copyright © 2007 Healthnotes, Inc. All rights reserved. www.healthnotes.com
Learn more about Healthnotes, the company.
Learn more about the authors of Healthnotes.
The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires September 2008.